Binding of the Origin Recognition Complex (ORC) to origins of replication marks the bandanas first step in the initiation of replication of the genome in all eukaryotic cells.Here, we report the structure of the active form of human ORC determined by X-ray crystallography and cryo-electron microscopy.The complex is composed of an ORC1/4/5 motor mod

BACKGROUND: The aim was to translate and develop a patient competence (PC) questionnaire in the context of cardiology and test its validity and reliability.METHODS: In total, 148 cardiac patients who have inclusion criteria of the study were completed cardiac PC (CPC) questionnaire.Hospital Anxiety and Depression Scale and self-administered instrum

http://dx.doi.org/10.5028/jatm.v5i1.192 The present work addresses a sensitivity analysis investigation of the aeroelastic stability margins for the VSB-30 sounding rocket during the atmospheric flight Bike Parts - Spokes phase.Parametric stability analyses are performed considering variations of the inertia properties of the modular payload.Such v

Alkaline soils commonly called as Usar soil having pH 7.5 to 11.0 is commonly found in regions having poor drainage and little percolation.These soils occupy vast tracts of barren lands in the northern parts of India.These areas are frequently visited by man and animals, however there are no reports on the occurrence of keratinophilic fungi from th

BackgroundInosine monophosphate (IMP) is naturally present in poultry muscle and plays a key role in improving meat flavour.However, IMP deposition is regulated by numerous genes and complex molecular networks.In order to excavate key candidate genes that may regulate IMP synthesis, we performed proteome and metabolome analyses on the leg muscle, c